https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30611 Corymbia and Angophora. Four Angophora and Corymbia species were evaluated for their phytochemical profile and efficacy against both primary and secondary pancreatic cancer cell lines. The aqueous leaf extract of Angophora hispida exhibited statistically higher total phenolic content (107.85 ± 1.46 mg of gallic acid equiv. per g) and total flavonoid content (57.96 ± 1.93 mg rutin equiv. per g) and antioxidant capacity compared to the other tested eucalypts (P < 0.05). Both A. hispida and A. floribunda aqueous extracts showed statistically similar saponin contents. Angophora floribunda extract exerted significantly greater cell growth inhibition of 77.91 ± 4.93% followed by A. hispida with 62.04 ± 7.47% (P < 0.05) at 100 μg/ml in MIA PaCa-2 cells with IC₅₀ values of 75.58 and 87.28 μg/ml, respectively. More studies are required to isolate and identify the bioactive compounds from these two Angophora species and to determine their mode of action against pancreatic malignancies.]]> Thu 09 Dec 2021 11:03:07 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12318 Sat 24 Mar 2018 08:11:35 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40451 Angophora, Corymbia, Eucalyptus) within Australia were assessed using IUCN Red List Categories and Criteria. Overall, 193 (23%) eucalypts qualified as threatened and 36 were considered Data Deficient. One hundred and thirty-four threatened species qualified under criterion A2, representing a past and irreversible population decline of >30%. The remainder were narrow-range species with ongoing threats (mostly mining or urbanisation), or naturally rare. Habitat conversion to crops and pastures was the cause of decline for most threatened eucalypts. Threatened species were concentrated where deforestation and high eucalypt richness coincide, especially south-western Western Australia. Corymbia or Angophora species, and relatively few tropical eucalypts are threatened. Fire, timber harvesting and disease were rarely sufficient threats to eucalypts to warrant a threatened status. Sheep grazing limits regeneration in temperate woodlands, but requires further quantification for individual species. Prior to this study, 89 eucalypts were listed as threatened under Australian environmental law. This assessment recommends that 32 of these species be downgraded to Near Threatened or Least Concern. A further 11 species were identified as Data Deficient, while an additional 147 species were proposed for listing as threatened. This systematic assessment of Australian eucalypts emphasises the importance of decline rather than rarity when compared with previous listings, with broad implications for listing long-lived plants in deforested landscapes.]]> Fri 22 Jul 2022 14:58:21 AEST ]]>